COVID-19 Computer-aided Diagnosis through AI-assisted CT Imaging Analysis: Deploying a Medical AI System (preprint)

Computer-aided diagnosis (CAD) systems stand out as potent aids for physicians in identifying the novel Coronavirus Disease 2019 (COVID-19) through medical imaging modalities. In this paper, we showcase the integration and reliable and fast deployment of a state-of-the-art AI system designed to automatically analyze CT images, offering infection probability for the swift detection of COVID-19. The suggested system, comprising both classification and segmentation components, is anticipated to reduce physicians' detection time and enhance the overall efficiency of COVID-19 detection. We successfully surmounted various challenges, such as data discrepancy and anonymisation, testing the time-effectiveness of the model, and data security, enabling reliable and scalable deployment of the system on both cloud and edge environments. Additionally, our AI system assigns a probability of infection to each 3D CT scan and enhances explainability through anchor set similarity, facilitating timely confirmation and segregation of infected patients by physicians.

Domain adaptation, Explainability & Fairness in AI for Medical Image Analysis: Diagnosis of COVID-19 based on 3-D Chest CT-scans (preprint)

The paper presents the DEF-AI-MIA COV19D Competition, which is organized in the framework of the 'Domain adaptation, Explainability, Fairness in AI for Medical Image Analysis (DEF-AI-MIA)' Workshop of the 2024 Computer Vision and Pattern Recognition (CVPR) Conference. The Competition is the 4th in the series, following the first three Competitions held in the framework of ICCV 2021, ECCV 2022 and ICASSP 2023 International Conferences respectively. It includes two Challenges on: i) Covid-19 Detection and ii) Covid-19 Domain Adaptation. The Competition use data from COV19-CT-DB database, which is described in the paper and includes a large number of chest CT scan series. Each chest CT scan series consists of a sequence of 2-D CT slices, the number of which is between 50 and 700. Training, validation and test datasets have been extracted from COV19-CT-DB and provided to the participants in both Challenges. The paper presents the baseline models used in the Challenges and the performance which was obtained respectively.

A Deep Neural Architecture for Harmonizing 3-D Input Data Analysis and Decision Making in Medical Imaging (preprint)

Harmonizing the analysis of data, especially of 3-D image volumes, consisting of different number of slices and annotated per volume, is a significant problem in training and using deep neural networks in various applications, including medical imaging. Moreover, unifying the decision making of the networks over different input datasets is crucial for the generation of rich data-driven knowledge and for trusted usage in the applications. This paper presents a new deep neural architecture, named RACNet, which includes routing and feature alignment steps and effectively handles different input lengths and single annotations of the 3-D image inputs, whilst providing highly accurate decisions. In addition, through latent variable extraction from the trained RACNet, a set of anchors are generated providing further insight on the network's decision making. These can be used to enrich and unify data-driven knowledge extracted from different datasets. An extensive experimental study illustrates the above developments, focusing on COVID-19 diagnosis through analysis of 3-D chest CT scans from databases generated in different countries and medical centers.

AI-MIA: COVID-19 Detection & Severity Analysis through Medical Imaging (preprint)

This paper presents the baseline approach for the organized 2nd Covid-19 Competition, occurring in the framework of the AIMIA Workshop in the European Conference on Computer Vision (ECCV 2022). It presents the COV19-CT-DB database which is annotated for COVID-19 detction, consisting of about 7,700 3-D CT scans. Part of the database consisting of Covid-19 cases is further annotated in terms of four Covid-19 severity conditions. We have split the database and the latter part of it in training, validation and test datasets. The former two datasets are used for training and validation of machine learning models, while the latter will be used for evaluation of the developed models. The baseline approach consists of a deep learning approach, based on a CNN-RNN network and report its performance on the COVID19-CT-DB database.

MIA-COV19D: COVID-19 Detection through 3-D Chest CT Image Analysis (preprint)

Early and reliable COVID-19 diagnosis based on chest 3-D CT scans can assist medical specialists in vital circumstances. Deep learning methodologies constitute a main approach for chest CT scan analysis and disease prediction. However, large annotated databases are necessary for developing deep learning models that are able to provide COVID-19 diagnosis across various medical environments in different countries. Due to privacy issues, publicly available COVID-19 CT datasets are highly difficult to obtain, which hinders the research and development of AI-enabled diagnosis methods of COVID-19 based on CT scans. In this paper we present the COV19-CT-DB database which is annotated for COVID-19, consisting of about 5,000 3-D CT scans, We have split the database in training, validation and test datasets. The former two datasets can be used for training and validation of machine learning models, while the latter will be used for evaluation of the developed models. We also present a deep learning approach, based on a CNN-RNN network and report its performance on the COVID19-CT-DB database.